The Healing Garden, a secret world that has provided treatment to heal the Earth, is under attack by the Byougenzu, who plan to infect Earth with an illness, putting it in great danger! To solve this crisis, the three medical trainees of Earth, known as the Healing Animals, along with Latte, who holds a special power as the Princess of the Healing Garden, escape in search of their partners! Three ordinary girls come across the group by chance, and together, they transform into Pretty Cure and take on the Byougenzu!

负责医治地球的异世界“治愈花园”被企图用疾病侵蚀地球的敌人“病幻者”袭击而陷入危机，地球亦陷入危机之中。 为了挽救这个危机，顺利逃走的3只“地球医生见习生”的“治愈动物”们，带着藏有神秘力量的治愈花园的公主拉特，前来地球寻找搭档。 三名普通少女与“治愈动物”相遇，变身成光之美少女，向“病幻者”宣战。 为了保护感应到“病幻者”的攻击而失去生机的拉特、重要的地球、还有在这里生长的所有生命，光之美少女们将结合所有治疗地球的力量！ 我们开始吧！光之美少女的作战！

负责医治地球的异世界“治愈花园”被企图用疾病侵蚀地球的敌人“病幻者”袭击而陷入危机，地球亦陷入危机之中。 　　为了挽救这个危机，顺利逃走的3只“地球医生见习生”的“治愈动物”们，带着藏有神秘力量的治愈花园的公主拉特，正在前去寻找拍挡。 　　三名普通少女先后遇到“治愈动物”，变身成光之美少女，向“病幻者”宣战。 　　感应到“病幻者”的攻击而失去生机的拉特，重要的地球，还有在这里生长的所有生命，抱持保护这一切的感情的光之美少女，现在，把治疗地球的力量结合起来吧！ 　　那开始吧！光之美少女的作战！

Tsubomi Hanasaki is a girl in the second grade of middle school who likes flowers and plants. One day she experiences a weird dream. In that dream, a large blooming tree appears. Suddenly, it loses all of its flowers and 2 fairies appear. A few days later after Tsubomi has transferred to Myoudou Academy, suddenly the fairies from the dream appear before her and plead to Tsubomi to become the legendary warrior Pretty Cure, and protect the Heart Tree. However, Tsubomi declines as she doesn't think that she would be able to do that. However, a mysterious enemy suddenly strikes and steals the Heart Flower of her classmate, Erika Kurumi. Now she doesn't have a choice. To retrieve Erika's Heart Flower, she has to transform into a Pretty Cure and fight. Working up the courage, Tsubomi turns into Cure Blossom and a new chapter of Pretty Cure begins!

Hibiki and Kanade are two friends who grew up together in Kanon Town. Very different in their personalities, they share one thing in common: A connection to music. No matter how different they are or how much their differences cause them to quarrel, they both continue to share loving hearts. One day they meet Hummy, who is sent to the Human World from Major Land to collect the scattered notes of the Melody of Happiness. They have to instantly transform into Pretty Cures to resist the threats and evil music from Mephisto. Can they stop the Melody of Sorrow from disrupting their peaceful town, and can their warped friendship measure up to the bonds of Pretty Cure?

Mirai Asahina, a thirteen-year-old girl who is excited by various things, goes with her stuffed bear, Mofurun, to investigate a mysterious object that fell from the sky. There, she meets a young magician named Liko who is searching for something known as the Linkle Stone Emerald. When dark servants of Dokuroxy come seeking the Linkle Stone Emerald, Mirai and Liko join hands with Mofurun and transform into the legendary magicians known as the Pretty Cures to fight against them. Thus, Mirai joins Liko in attending Magic School, where they must learn how to use magic while also fighting off Dokuroxy's minions.

Nozomi Yumehara, a regular student, finds a magical book called the Dream Collet in the library and meets Coco and Nuts, two creatures from the Palmier Kingdom. They plead with Nozomi to restore their world, which has been destroyed by an organization called the Nightmares, by completing the Dream Collet and finding the 55 Pinkies to make any wish come true. Meanwhile, the Nightmares are moving into the real world. Once Nozomi agrees to help, Coco and Nuts transform her into the legendary warrior Cure Dream and turn four fellow students into her Pretty Cure team.

During the summer festival five years ago, two girls met at a mysterious tree and saw two glowing spheres. Now, these two girls--Saki Hyuga, ace pitcher on the school softball team; and Mai Mishou, who prefers sketching over stargazing--are chosen by the spirits of flowers (Flappy) and birds (Choppy) to restore the Seven Fountains and save their worlds from Dark Autumn. Together, they are the NEW Pretty Cure.

Good Job, Good Job also known as Cheer Up on Love, Job Well Done, Well Done or Thumbs Up For A Job Well Done is a South Korean television series that aired on MBC, its first aired on March 14, 2009 and finished on August 2, 2009 and the first shown in South Korea.

《光之美少女》系列下一部剧场版《Healin' Good ♥ 光之美少女》，预计在2021年上映。